Top 10 Ways Science Could Extend Your Lifespan - An inevitable part of life is aging and dying. It’s part of Newton’s second law of thermodynamics, which is that objects have to go from order to disorder. But there are a number of researchers who are trying to break those rules and they are trying to extend life spans for decades, centuries, or even stop aging and death altogether. 10. Elysium Health’s Basis Pill Leonard Guarente, a leading MIT biologist, with the backing of five Nobel Laureates, launched the start-up company Elysium Health in 2015. Their first pill, Basis, works at a cellular level and it enables the body to produce a natural compound called nicotinamide adenine dinucleotide (NAD), which is an important compound that supports a healthy metabolism. The active ingredient in the blue pill is nicotinamide riboside, which is a substance that helps make NAD in the body. The tests have shown better health in older mice, but the problem with Basis is that there is no proof that it works in humans. Testing something like longevity in humans could take decades. So with that being said, Basis is available for sale through their website. If you take two gel caps a day, it will cost you $60 a month with a $50 membership. 9. Sirtuin Humans, like other mammals, have seven types of proteins in their bodies called sirtuins, or sir2, and they are labeled SIRT1 to SIRT7. Researchers aren’t exactly sure what they do, but there is some evidence that they may have a role in preventing chronic diseases like heart disease and cancer. An example of how sirtuins works is Resveratrol, which is the nutrient that is found in grape skins and red wine, and it has been known to help with heart health. It is believed to be beneficial because it may activate the SIRT1 gene, which makes more SIRT1 protein, and that protein helps the heart. In 2012, Scientists at Bar-Ilan University in Israel published a study about the use of SIRT6 on mice. Their study found that the males lived 16 percent longer than untreated mice. The females didn’t show the same results, and the researchers are unsure why exactly, but one possible reason that they speculated is that male mice have a higher rate of cancer, so the SIRT6 could work as a tumor suppressor, which would have a greater effect on the male population. While a lot of research still needs to be done, researchers are hopeful that SIRT6 or one of the other sirtuins may unlock the key to longevity. Until then, you may just have to drink red wine to activate SIRT1 so you can have a healthier heart. →Subscribe for new videos every day! http://bit.ly/toptenzsubscribe →10 Reasons Bruce Lee was a Superhuman: http://bit.ly/1Hl4mVu →Simon's VLOG: http://bit.ly/1mJlVdR Entertaining and educational top 10 lists from TopTenzNet! Brand new videos 7 days a week! Videos are published at 6pm EST every day! Subscribe to our Facebook: https://www.facebook.com/TopTenz/ Other TopTenz Videos: Top 10 Planets That Could Potentially Sustain Life http://bit.ly/1RN7fmv Top 10 Facinating Facts About Black Holes http://bit.ly/1Y1Uyc4 Text version: http://www.toptenz.net/10-technologie... Coming up: 10. Elysium Health’s Basis Pill 9. Sirtuin 8. Young Blood 7. Cellular Compound 6. Telomerase 5. AMPK 4. Calico LLC 3. Strategies for Engineered Negligible Senescence Research Foundation 2. Bioprinting 1. The 2045 Initiative Source/Further reading: https://youtu.be/y1AIrm58m10 https://www.bostonglobe.com/business/... http://www.technologyreview.com/news/... http://www.elysiumhealth.com/product-... https://youtu.be/pfa0hgwiPbI http://www.livescience.com/18593-anti... http://www.mayoclinic.org/diseases-co... https://youtu.be/yKLlXRjktak https://www.newscientist.com/article/... http://news.sciencemag.org/biology/20... http://www.nature.com/news/young-bloo... http://news.sciencemag.org/biology/20... https://youtu.be/KE-og-W-7ps http://www.livescience.com/16845-long... http://blogs.scientificamerican.com/g... http://learn.genetics.utah.edu/conten... http://www.sciencedaily.com/releases/... https://youtu.be/MO04TOaGOog http://newsroom.ucla.edu/releases/ucl... http://www.forbes.com/sites/melanieha... http://googlepress.blogspot.ca/2013/0... https://youtu.be/D1jaAMLg3uI http://www.sens.org/research/introduc... https://youtu.be/9D749wZSlb0 http://www.livescience.com/52571-3d-p... https://youtu.be/f9e5dmmyxSw http://www.livescience.com/37499-immo... http://motherboard.vice.com/blog/russ...

Comments

1. It's a lot of work to stay alive and will be a lot more work keep to on living...work,work,work...better love what you do in life.
2. Wat about lecithinium
3. Smart Dieting (which could include supplements for those of us who want our cake and eat it too) and Good Exercise seem to be at the root of a lot of these.
   
   #10. Increase NAD naturally by giving your body the components of (Tryptophan) * (Aspartic Acid) * (Niacin aka B3). Niacin may be the most important because of it's other health benefits that are more extensive than the other two. The supplement the company is making, though I think is desirable, is essentially trying to unlock the "cheat" way to caloric restriction and extremely disciplined dieting.
   
   High_Tryptohpan_Foods = ["Spinach", "Seaweed", "Soy", "Egg Whites", "Sea Lion Kidneys"]
   High_AsparticAcid_Foods = ["Soy Isolate Protein", "Raw Egg Whites", "Asparagus", "Tuna", "Chicken", "Oat Bran"]
   High_Niacin_Foods = ["Liver", "Chicken", "Tuna", "Spinach", "Kale", "Avocado", "Mushrooms", "Brewers Yeast"]
   
   #9.
   Some_Top_SirtFoods = ["Kale", "Omega3 Fish Oil", "Turmeric", "Parsley", "Celery", "Oranges", "Lemons", "Soy", "Extra Virgin Olive Oil"]
   
   #5. Talking about AMPK ultimately leads to talking about "autophagy" and cleansing your body of junk. Autophagy is a type of "Acute" stress response.
   
   Main_Autophage_Processes = ["Caloric Restriction (20% - 40%)", "Intermittent Fasting", "HIIT Exercises (30-80 min.)", "High Quality Fats Ketogenic Diet"]
   
   Autophagic_Ketogenic_Diet = {"Good fats" : High, "Protein" : Moderate, "Non-Fiber Carbs": Extremely_Low}
   
   #3. I think the following relates to #5: "ApoptoSENS", "AnyloSENS", and "LysoSENS." MitoSENS relates to #10, #7, & #6. ReplinSENS relates to #10, #9, #8(?), & #4.
   
   I also like how #3's Dr. de Grey is taking good "Oxidation Management" practices to his head, damning common culture :)
4. all these researches are usless ,the real life source lies in heart beat and human soul, these 2 inside of us keep going us alive as usual ,messing with this god placement system makes only getting you in deep no going back demage of your life ,don't liston these scientist experiments ,life you r having today is a gift human being may have increasing it by preventing himself by using bad things ,sex,smokings, wine , drugs , glass etc getrid all these bad things then you may have life even biger but most of specially americans involved by drinking too much wine in there daily life even there kids are involved .
5. @toptenz if you are reading this, I privately have contemplated a few of the topics that have popped up in this video. Before watching it, I thought I was the only one to think of this. but seeing as my immortality theory has appeared in several listing on here, I should really be trying to contact that rich guy and confirm a few things. But I will share a lesson I learned in all of this, be careful playing God. These are his designs, we just animate them...
6. yes, the #1 is already a reality.
   https://www.youtube.com/watch?v=xg29TuWo0Yo
7. Many movies show AI robots exterminating the human race.
   So we decided to make ourselves the robots.
   *clap* *clap*
8. 1. "Jesus is the answer to eternal life, we'll achieve it once we're in heaven" - Natural Selection speaks for itself! I'm not gonna try to discourage the deeply religious into dying out! KEEP UP THE GOOD WORK, THEISTS!
   
   2. "If we live forever we will have to see our love ones die before us" - No thanks to you assholes for giving that idea to our loved ones!
   
   3. "It's impossible to live forever, so why even try? " - Not up to the challenge of trying to find out all by yourself, are we? Jeez! It's not like you have anything better to do with your life?
   
   4. "Immortality will cause overpopulation" - Either achieve it by mind-uploading or DON'T HAVE FUCKING KIDS if you want extended lifespans but you're worried about overpopulation.
   
   5. "The longer I live, the more boring it would be" - Speak for yourself! There are a seemingly infinite number of information out there, and here you are getting "bored" because you think you already know it all!
   
   6. "you could try to copy your mind onto a pc but it's just a copy"' - maybe so? But at least you'll be leaving a legacy, like having a child that will, at 100%, finish whatever you have started.
   
   7. "There is no reason to fear death, it's just a part of life" - Who says that all of us fear death? We just wanna challenge ourselves on how long are we gonna last until we die (in case that death really is inevitable).
   
   8."You're just wasting your time attempting to live forever" - Like I said at #2! It's not like you have anything better to do with your life? I mean YOU LITERALLY ARE NOT GONNA THE GUY WHO'S GONNA HAVE THE LAST LAUGH!!!
   
   9. "Maybe not forever, but a hundred years is way too little" - That kind of mentality, I can respect! But don't pull me down with you in case I still wanna live. Otherwise, I'll be the one who's gonna give you an "early retirement".
   
   10. "But we don't wanna live forever" - We don't care! But some of us wanted the opposite, and you shouldn't care either!
   
   11. "Humans are not made to be immortal. You would get bad shit insane." - Says the mortal! Why? Did a thousand year-old man in perfect shape told you that?
   
   12. "But the universe itself wouldn't last forever" - That's big talk for a guy who lived less than 80 years! We're not even sure about the limits this reality has?
   
   14. Why not prioritize the sick and the poorer ones first? - Why not both? JESUS FUCKING CHRIST! NOBODY FUCKING MENTIONED THAT LIFE-EXTENSION SHOULD BE OUR ONLY PRIORITY!
   
   15. "People are just dumb, who are they to choose eternal life over death?" - We're the kind who has a choice! Not given to us, but what we bestowed amongst ourselves!
   
   16.Cancer cells are immortal, and look how it destroys the body" - Luckily you're not just a simple cell that is only programmed to replicate, are you?
   
   17. "But our population isn't yet ready for an increased lifespan. We have to get them in order, first" - Fine! But some of us who long for creating a better civilization needs this ASAP! So, I'm cool with it as long as those minorities gets access to this (including me)!
9. Screw machines! I want cloning!
10. Wait! This is the toptenz YouTube channel? I thought I was on pornhub watching midget fart porn.
11. You really sound like white South Africans, those who got British ancestory.
12. So basically number one eliminates the soul.
13. "playing god" "we weren't made to live forever"
    
    then you don't seek medical care and die of childbirth at 17. other people have every right to make our own health decisions.
    
    I support both euthanasia and indefinite life extension. 100% pro choice on everything that's a personal choice. abortion, drug use, Sex work, if you want to live or die etc
14. no.1 is crazy ppl thing
15. WOAH 2045 INITIATIVE. That is so cool. I wanna be a robot
16. luckily ill be 45 at that year
17. Once the "silver pill" to extend life with 30% will be discovered and affordable, the social crisis will reach an uncontrollable level. The human society is not prepared to handle an overpopulated Earth, the working force will be smaller and smaller due to technological advancement, therefore more and more people will not be employed. The pension and welfare plans will crush under the fiscal and political system we're in. Just make the extrapolation on other domains taking as an example the agricultural activity, essential for life: 1.9% of the population in 2016 from 80% in 1890.
18. Number One is... uhh, not what I would want really. I value being well, an organic life form. Being able to fully interface with Technology and Synthetics, thats cool. But if we were to live forever, I'd want a human like and organic body to do that in.
    I do wonder how frustrating and boring it would get living forever, but maybe if we found some way to sleep for an extremely long period of time, and even dream whilst doing so, then that would be great.
19. this been going on since like the 90s
20. is this april fools XD ?